Watch the Running Man online guitar lesson by Jon Finn from 30 Melodic Modal Rock Licks You MUST Know
This one takes advantage of hammer-ons, pull-offs, and the open B string to achieve a "running up and down the neck" sound (hence the title of the lick). One big thing to pay attention to here is keeping the timing to a nice, even 16th note rhythm feel.
At the end, it's important to position your hand for that end scale pattern. The last three notes are a little tricky because you use your pinky to get the 11th, then 12th frets, then the 3rd finger for the very last note.