Watch the No Walkin' Blues online guitar lesson by Carl Verheyen from S.W.A.T. Rhythm
I've played this song many times over the last 15 plus years and I never do it the same way twice. I can always get a groove going with the thumping bass part of the riff and some of the turnarounds are worth noting. If you want to learn the basic riff, try it at a slow tempo and bring it up to foot stomping tempo. There is an entire style of blues guitar called "Piedmont Blues" where the guitarist attempts to emulate a stride piano. This hints at the Piedmont style in places and is especially effective on acoustic guitar.