Watch the Mel Rhythm online guitar lesson by TrueFire from Play Rock Guitar 4: Rhythm Approaches
Mel Rhythm - Variations is a video guitar lesson presented by Jeff Scheetz and is sourced from Blues-Rock: Secret Sauce.
There are so many different inversion possibilities that you should NEVER be bored again with a static progression. However, it does help to work a few playable shapes out ahead of time. Keep a bunch of inversion patterns ready at your disposal much in the same way you keep your bag of tricks filled with a bunch of lead licks.