Watch the Using Fragments online guitar lesson by TrueFire from Play Rock Guitar 10: Advanced Soloing Approaches
Using Fragments - Concept 20 is a video guitar lesson presented by Shane Theriot and is sourced from Solo Mojo.
Another approach is to use what I call "fragments." These are ideas that can be moved around the neck at random and interspersed with your other ideas to mix things up. Here's one that is a hybrid of an idea that I got from Al Dimeola.