The main thing I can say when working on "Fishin' Blues" is to play with intensity. Really commit to the groove, feel, and notes. Take this opportunity, especially on the louder parts, to really dig into the strings to get that blues rock sound out of the guitar. The attack and timbre of note is essential for this tune to sound right. When I go to the softer section, I roll my volume knob back to clean up the guitar's signal, playing softer but still maintaining the same intensity in the playing.
I'm always thinking about the groove and looking to the drummer, so listen to the jam track and pay attention to the drums. Where is the kick and snare in the beat? Ask yourself, "am I locked in or not?" I HIGHLY suggest you record yourself playing the tune back and listen. Does it "make your big toe wanna stand up in your boot" as Little Richard said about Jimi?
I didn't mention what effects I was using in the video, but I have an amp (Marshall 2061x) that's distorting my sound, a fuzz pedal, and a delay as well.