Watch the Performance Studies online guitar lesson by TrueFire from Play Blues Guitar 4: Rhythm Approaches
In this section of Performance Studies you will complete several whole songs, like Stormy Monday and Sweet Home Chicago, which is of course the goal of playing - to be able to get all the way through tunes.
TIP! Whatever you sit down to practice on, remember, breaking it down into small chunks will help you play it better, and remember it better. Take a lick or rhythm or pattern and see if you can break it down. Maybe you can look at what your right hand is doing, then what your left hand is doing. Look at each little technique involved and work on those individually. Once you have all the little pieces sounding good - then glue it all back together and voila! You will find that the whole has been strengthened by working on each little part!