Watch the Jazz in Blues online guitar lesson by TrueFire from Play Blues Guitar 10: Advanced Soloing Principles
In this section you will take your blues in a decidedly jazzy direction. You'll learn some funky and "Wes" style moves, and then look at the diminished scale and the melodic minor scale and learn how and when to apply them to the blues.
TIP! The key to having great soloing and improvisation chops is continuing to build on your basic soloing foundation. So you should be working on things like targeting notes, making sure you are playing the best possible note you can. This requires you to be knowledgeable about what the chords are doing underneath your solo. That is one of the things beginning soloists don't do enough of is pay attention to the chord progression they are playing over. You also have to keep your technique sharp - it is not good knowing all the right notes to play if you are sloppy and can't get to them in time. So while you have to work on the knowledge side of music to really advance your improv, you still have to be spending some time working with a metronome and pushing your physical limits as well.