Watch the The Major 2nd online guitar lesson by Frank Vignola from Jazzin' the Blues Vol. 1
In this set, we add the major 2nd to the blues pentatonic scale. We use a Bb min blues progression for this one.
I stay scalar and melodic using the 2nd. In the second chorus, I use a flourish and some double stops. This one note addition to the blues scale can help you become more melodic in your blues playing.