Watch the Heart and Soul online guitar lesson by Mimi Fox from Graduated Solos
Wes Montgomery/B.B. King/Carlos Santana/Eddie Van Halen/Julian Bream/Sharon Isbin/Joe Pass/Charlie Christian - just a few great players in very different genres that all share one thing: a complete devotion to the music they are playing, and the ability to communicate their heart/soul at a given moment in time through the music. I don't particularly care for all of these artists, but there is no denying the emotional impact they have on listeners. Again, don't be fooled into thinking it's enough to play your axe well... that is merely the jumping off point!! The real stuff is how you put your heart/soul/spirit into each note you play.
So play a lot,and play from your heart!