Watch the Blues Chord Solo online guitar lesson by Mimi Fox from Flying Solo
Remember as you begin to structure your own chord solos, that each idea must lead logically into the next idea. If you have played an unusual harmony on one chord, try answering that voicing with another, maybe similar voicing, or see what it sounds like to play something completely unrelated. Sometimes that can be cool, sometimes not so cool... use your ears and let them guide you. The same is true if you play a cool rhythmic figure for one chord. You could answer yourself with a similar rhythmic idea, or go completely in another direction and see how that sounds. It's a good idea to tape yourself practicing and see what you come up with.