Watch the Ham's Boogie in A 1 online guitar lesson by TrueFire from Acoustic Guitar Explorations
Lesson Source: David Hamburger's Fingerstyle Blues Factory
I mentioned earlier how palm muting can really help you distinguish the alternating bass part from the melodic licks on top. In an arrangement like "Ham’s Boogie," you can also use dynamics to distinguish the main melodic statements, or the “call” phrases, from the more purely rhythmic phrases, or “responses.”
Basically, you want to play more emphatically and really bring out the melody in measures 1-2, 5-6, and 9-12, while dropping back dynamically to play a little quieter overall in measures 3-4, 7-8, and 13-16. The repeated "Magic Sam" phrases will take on a thematic feel while provide breathing room throughout the chorus, which in turn will make the melodic phrases really pop with the clarity of a solo instrument or lead vocal.