Watch the At Night online guitar lesson by Corey Congilio from Slow Blues Guru
The coolest thing about this solo to me is the use of open strings. When you're in the key of E, you have plenty of open strings to work with. You'll notice that I jump into that right at the start. Near the end of the solo I let the high E string drone through lots of the phrases. This is something you may not have done before, so give it a shot! To get that aggressive bluesy tone, I'm using a Tweed Fender Deluxe amp model and my SG! I think it's a good combo!