Watch the Freddie Free Solo 1 online guitar lesson by Chris Buono from Guitar Lab: Blues Soloing
In the first chorus you'll really be committing to the rhythm by playing right on the entrance and exit of the chords, and at the same time, playing the respective primary chord tones. Keep this idea in mind as it will work in your favor big time in initial choruses of multi-chorus soloing excursions. This approach will have you come into your solo with a tasteful, reserved entrance that screams, "A seasoned player is in the house!" That not only grabs the attention of the audience, but also the musicians you're playing with and that's ALWAYS a good thing.