Watch the Blues Techniques 16 online guitar lesson by Brad Carlton from Bluesology 2

Ever wonder how much mileage you could get out of a three note lick? Well, let's explore some possibilities by rearranging the notes in an idea, substituting a note with another, placing a note in another octave, perhaps another string - the combinations are infinite.
If you're aware of the scale degrees that your ideas are derived from, transposing them to other keys won't be a problem.
Microtonal bends between the flat 3 to 3, flat 5 to 5, and flat 5 to 4 will increase the possibilities for melodic variation and add a very impactful singing quality to your playing.