Watch the Sam I Am online guitar lesson by David Hamburger from Blues Alchemy: Post-War

In my experience, “how do I get out of the pentatonic box?” is one of the questions we blues guitarists ask most (the other two being “maybe some new gear would solve the problem?” and “where can we get breakfast at 2:30am?”). So while you could (and maybe should) spend some time checking out how Lightnin’ Hopkins would actually play on a tune like this, the next step is to look at things a little more generally: “What else can you do on a tune like this?” So that ultimately, you can ask the most important question, which is: “How would I play on a tune like this?”