Watch the Not Too Terrible online guitar lesson by Corey Congilio from 50 Progressive Blues Licks You MUST Know
This lick will take you to bar 5 of a 12 bar blues progression. What's nice about this lick is it's going to weave its way through the II-V progression in what's often called a jazz/blues. A jazz/blues progression consists of I-IV-V chords but also usually contains a II, VI, and even a diminished chord. Listening to these progressive blues players will open up your ear to more advanced progressions and tunes.
Learn a good 12 bar jazz/blues progression and try this lick over it.