Watch the Up Picks online guitar lesson by Jeff McErlain from 30 Smokin' Blues-Rock Guitar Licks You MUST Know
Here's a slick little blues lick that uses a lot of up picks. You have the tab and the video, so have at it.
Here, I want to discuss gear. I love gear, to a fault, but let me tell you a story that changed everything for me. I was at a Jeff Beck (The Master) concert in 1999, and he was in the middle of playing "Where Were You" and his Marshall amp broke down. Silence. His tech then plugs him into a Fender Twin (one of my least favorite amps personally) and The Master starts playing. HE SOUNDED EXACTLY THE SAME. EXACTLY.
Tone is in your hands! Yes, you need a decent amp and guitar, but once that's taken care of, it's all you baby. It's about how you pluck and fret those notes. Take your time and get a big tone. To me it's everything. That and playing in tune...oh yeah, and in time. Yup, that's it. For the most part.