Watch the Walk the Bass online guitar lesson by Joe Dalton from 50 Acoustic Blues Licks You MUST Know
Here’s a good example of what you can do with variations. The melody from example 1 is now the bass line. This is a good start for creating a walking bass line. Notice the subtle use of the open strings. Although they are used sparsely, these single open notes add a lot to the feel. I often use this pattern to move from the 1 chord to the 4 chord or from 5 to 1.